Compound loss of GSDMD and GSDME function is necessary to achieve maximal therapeutic effect in colitis

Gasdermin D (GSDMD) and gasdermin E (GSDME) perpetuate inflammation by mediating the release of cytokines such as interleukin-1β (IL-1β) and IL-18. However, not only are the actions of GSDMD in colitis still controversial, but its interplay with GSDME in the pathogenesis of this disease has not been...

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Detalles Bibliográficos
Autores principales: Xiao, Jianqiu, Sun, Kai, Wang, Chun, Abu-Amer, Yousef, Mbalaviele, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463374/
https://www.ncbi.nlm.nih.gov/pubmed/36097634
http://dx.doi.org/10.1016/j.jtauto.2022.100162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463374/
https://www.ncbi.nlm.nih.gov/pubmed/36097634
http://dx.doi.org/10.1016/j.jtauto.2022.100162

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