Comparison of actionable events detected in cancer genomes by whole-genome sequencing, in silico whole-exome and mutation panels

BACKGROUND: Next-generation sequencing is used in cancer research to identify somatic and germline mutations, which can predict sensitivity or resistance to therapies, and may be a useful tool to reveal drug repurposing opportunities between tumour types. Multigene panels are used in clinical practi...

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Detalles Bibliográficos
Autores principales: Ramarao-Milne, P., Kondrashova, O., Patch, A.-M., Nones, K., Koufariotis, L.T., Newell, F., Addala, V., Lakis, V., Holmes, O., Leonard, C., Wood, S., Xu, Q., Mukhopadhyay, P., Naeini, M.M., Steinfort, D., Williamson, J.P., Bint, M., Pahoff, C., Nguyen, P.T., Twaddell, S., Arnold, D., Grainge, C., Basirzadeh, F., Fielding, D., Dalley, A.J., Chittoory, H., Simpson, P.T., Aoude, L.G., Bonazzi, V.F., Patel, K., Barbour, A.P., Fennell, D.A., Robinson, B.W., Creaney, J., Hollway, G., Pearson, J.V., Waddell, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463385/
https://www.ncbi.nlm.nih.gov/pubmed/35849877
http://dx.doi.org/10.1016/j.esmoop.2022.100540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463385/
https://www.ncbi.nlm.nih.gov/pubmed/35849877
http://dx.doi.org/10.1016/j.esmoop.2022.100540

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