Pgc-1α controls epidermal stem cell fate and skin repair by sustaining NAD(+) homeostasis during aging

OBJECTIVE: The epidermal barrier is renewed by the activation, proliferation, and differentiation of keratinocyte stem cells after injury and aging impedes this repair process through undefined mechanisms. We previously identified a gene signature of metabolic dysfunction in aged murine epidermis, b...

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Detalles Bibliográficos
Autores principales: Wong, Wesley, Crane, Elizabeth D., Zhang, Hui, Li, Jiahe, Day, Tovah A., Green, Alex E., Menzies, Keir J., Crane, Justin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463389/
https://www.ncbi.nlm.nih.gov/pubmed/35987498
http://dx.doi.org/10.1016/j.molmet.2022.101575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463389/
https://www.ncbi.nlm.nih.gov/pubmed/35987498
http://dx.doi.org/10.1016/j.molmet.2022.101575

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