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Pgc-1α controls epidermal stem cell fate and skin repair by sustaining NAD(+) homeostasis during aging
OBJECTIVE: The epidermal barrier is renewed by the activation, proliferation, and differentiation of keratinocyte stem cells after injury and aging impedes this repair process through undefined mechanisms. We previously identified a gene signature of metabolic dysfunction in aged murine epidermis, b...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463389/ https://www.ncbi.nlm.nih.gov/pubmed/35987498 http://dx.doi.org/10.1016/j.molmet.2022.101575 |