TOB1 attenuates IRF3-directed antiviral responses by recruiting HDAC8 to specifically suppress IFN-β expression

Interferon regulatory factor 3 (IRF3) is a key transcription factor required for the secretion of type I interferons (IFN-α/β) and initiation of antiviral immune response. However, the negative feedback regulator of IRF3-directed antiviral response remains unknown. In this study, we demonstrated tha...

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Detalles Bibliográficos
Autores principales: Yu, Zhongxia, Wang, Lijuan, Zhao, Jing, Song, Hui, Zhao, Chunyuan, Zhao, Wei, Jia, Mutian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463440/
https://www.ncbi.nlm.nih.gov/pubmed/36085336
http://dx.doi.org/10.1038/s42003-022-03911-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463440/
https://www.ncbi.nlm.nih.gov/pubmed/36085336
http://dx.doi.org/10.1038/s42003-022-03911-x

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