CtIP-dependent nascent RNA expression flanking DNA breaks guides the choice of DNA repair pathway

The RNA world is changing our views about sensing and resolution of DNA damage. Here, we develop single-molecule DNA/RNA analysis approaches to visualize how nascent RNA facilitates the repair of DNA double-strand breaks (DSBs). RNA polymerase II (RNAPII) is crucial for DSB resolution in human cells...

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Detalles Bibliográficos
Autores principales: Gómez-Cabello, Daniel, Pappas, George, Aguilar-Morante, Diana, Dinant, Christoffel, Bartek, Jiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463442/
https://www.ncbi.nlm.nih.gov/pubmed/36085345
http://dx.doi.org/10.1038/s41467-022-33027-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463442/
https://www.ncbi.nlm.nih.gov/pubmed/36085345
http://dx.doi.org/10.1038/s41467-022-33027-z

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