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Role and mechanism of REG2 depletion in insulin secretion augmented by glutathione peroxidase-1 overproduction

We previously reported a depletion of murine regenerating islet-derived protein 2 (REG2) in pancreatic islets of glutathione peroxidase-1 (Gpx1) overexpressing (OE) mice. The present study was to explore if and how the REG2 depletion contributed to an augmented glucose stimulated insulin secretion (...

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Detalles Bibliográficos
Autores principales: Yan, Xi, Zhao, Zeping, Weaver, Jeremy, Sun, Tao, Yun, Jun-Won, Roneker, Carol A., Hu, Fenghua, Doliba, Nicolai M., McCormick, Charles Chipley W., Vatamaniuk, Marko Z., Lei, Xin Gen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463454/
https://www.ncbi.nlm.nih.gov/pubmed/36063729
http://dx.doi.org/10.1016/j.redox.2022.102457