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Dynamic S-acylation of the ER-resident protein stromal interaction molecule 1 (STIM1) is required for store-operated Ca(2+) entry

Many cell surface stimuli cause calcium release from endoplasmic reticulum (ER) stores to regulate cellular physiology. Upon ER calcium store depletion, the ER-resident protein stromal interaction molecule 1 (STIM1) physically interacts with plasma membrane protein Orai1 to induce calcium release–ac...

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Detalles Bibliográficos
Autores principales: Kodakandla, Goutham, West, Savannah J., Wang, Qiaochu, Tewari, Ritika, Zhu, Michael X., Akimzhanov, Askar M., Boehning, Darren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463532/
https://www.ncbi.nlm.nih.gov/pubmed/35934052
http://dx.doi.org/10.1016/j.jbc.2022.102303