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A chronic unpredictable stress protocol to model anhedonic and resilient behaviors in C57BL/6J mice

The complexity of the depressive symptoms observed in humans makes modeling depressive behavior in rodents challenging. Here, we present a highly reproducible protocol to generate mouse models that mimic several aspects of depression, namely anhedonia and loss of motivation. We describe acclimatizat...

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Detalles Bibliográficos
Autores principales: Bijata, Monika, Bączyńska, Ewa, Wlodarczyk, Jakub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463598/
https://www.ncbi.nlm.nih.gov/pubmed/36097387
http://dx.doi.org/10.1016/j.xpro.2022.101659