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A chronic unpredictable stress protocol to model anhedonic and resilient behaviors in C57BL/6J mice
The complexity of the depressive symptoms observed in humans makes modeling depressive behavior in rodents challenging. Here, we present a highly reproducible protocol to generate mouse models that mimic several aspects of depression, namely anhedonia and loss of motivation. We describe acclimatizat...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463598/ https://www.ncbi.nlm.nih.gov/pubmed/36097387 http://dx.doi.org/10.1016/j.xpro.2022.101659 |