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Effects of clot contraction on clot degradation: A mathematical and experimental approach

Thrombosis, resulting in occlusive blood clots, blocks blood flow to downstream organs and causes life-threatening conditions such as heart attacks and strokes. The administration of tissue plasminogen activator (t-PA), which drives the enzymatic degradation (fibrinolysis) of these blood clots, is a...

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Detalles Bibliográficos
Autores principales: Risman, Rebecca A., Abdelhamid, Ahmed, Weisel, John W., Bannish, Brittany E., Tutwiler, Valerie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463642/
https://www.ncbi.nlm.nih.gov/pubmed/35927957
http://dx.doi.org/10.1016/j.bpj.2022.07.023