IGHG3 hinge length variation was associated with the risk of critical disease and death in a Spanish COVID-19 cohort

IgG3 would play an important role in the immune adaptive response against SARS-CoV-2, and low plasma levels might increase the risk of COVID-19 severity and mortality. The IgG3 hinge sequence has a variable repeat of a 15 amino acid exon with common 4-repeats (M) and 3-repeats (S). This length IGHG3...

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Detalles Bibliográficos
Autores principales: López-Martínez, Rocío, Albaiceta, Guillermo M., Amado-Rodríguez, Laura, Gómez, Juan, Cuesta-Llavona, Elías, García-Clemente, Marta, Hermida-Valverde, Tamara, Enríquez-Rodriguez, Ana I., Hernández-González, Cristina, Martínez-Borra, Jesús, López-Larrea, Carlos, Gil-Peña, Helena, Alvarez, Victoria, Coto, Eliecer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463670/
https://www.ncbi.nlm.nih.gov/pubmed/36088493
http://dx.doi.org/10.1038/s41435-022-00179-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463670/
https://www.ncbi.nlm.nih.gov/pubmed/36088493
http://dx.doi.org/10.1038/s41435-022-00179-3

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