Cargando…

IGHG3 hinge length variation was associated with the risk of critical disease and death in a Spanish COVID-19 cohort

IgG3 would play an important role in the immune adaptive response against SARS-CoV-2, and low plasma levels might increase the risk of COVID-19 severity and mortality. The IgG3 hinge sequence has a variable repeat of a 15 amino acid exon with common 4-repeats (M) and 3-repeats (S). This length IGHG3...

Descripción completa

Detalles Bibliográficos
Autores principales:	López-Martínez, Rocío, Albaiceta, Guillermo M., Amado-Rodríguez, Laura, Gómez, Juan, Cuesta-Llavona, Elías, García-Clemente, Marta, Hermida-Valverde, Tamara, Enríquez-Rodriguez, Ana I., Hernández-González, Cristina, Martínez-Borra, Jesús, López-Larrea, Carlos, Gil-Peña, Helena, Alvarez, Victoria, Coto, Eliecer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463670/ https://www.ncbi.nlm.nih.gov/pubmed/36088493 http://dx.doi.org/10.1038/s41435-022-00179-3

Ejemplares similares

The FCGR2A rs1801274 polymorphism was associated with the risk of death among COVID-19 patients
por: López-Martínez, Rocío, et al.
Publicado: (2022)

Common mitochondrial haplogroups as modifiers of the onset-age for critical COVID-19
por: Vázquez-Coto, Daniel, et al.
Publicado: (2022)

Age-dependent effect of the IFIH1/MDA5 gene variants on the risk of critical COVID-19
por: Muñiz-Banciella, María G., et al.
Publicado: (2022)

Angiotensin-converting enzymes (ACE, ACE2) gene variants and COVID-19 outcome
por: Gómez, Juan, et al.
Publicado: (2020)

Association between the interferon-induced transmembrane protein 3 gene (IFITM3) rs34481144 / rs12252 haplotypes and COVID-19
por: Cuesta-Llavona, Elías, et al.
Publicado: (2021)

Variant-genetic and transcript-expression analysis showed a role for the chemokine-receptor CCR5 in COVID-19 severity
por: Cuesta-Llavona, Elías, et al.
Publicado: (2021)

Genetic variants in the NF-κB signaling pathway (NFKB1, NFKBIA, NFKBIZ) and risk of critical outcome among COVID-19 patients
por: Camblor, Daniel G., et al.
Publicado: (2022)

Transcriptomic clustering of critically ill COVID-19 patients
por: López-Martínez, Cecilia, et al.
Publicado: (2023)

Gene Variant in the NF-κB Pathway Inhibitor NFKBIA Distinguishes Patients with Psoriatic Arthritis within the Spectrum of Psoriatic Disease
por: Coto-Segura, Pablo, et al.
Publicado: (2019)

DNA genotyping of the ABO gene showed a significant association of the A-group (A1/A2 variants) with severe COVID-19.
por: Gómez, Juan, et al.
Publicado: (2021)

Effects of IFIH1 rs1990760 variants on systemic inflammation and outcome in critically ill COVID-19 patients in an observational translational study
por: Amado-Rodríguez, Laura, et al.
Publicado: (2022)

KCNH2 p.Gly262AlafsTer98: A New Threatening Variant Associated with Long QT Syndrome in a Spanish Cohort
por: Lorca, Rebeca, et al.
Publicado: (2022)

Sex susceptibility to ventilator-induced lung injury
por: López-Alonso, Inés, et al.
Publicado: (2019)

The Region Centromeric to HLA-C Is a Key Region for Understanding the Phenotypic Variability of Psoriatic Arthritis
por: Queiro, Rubén, et al.
Publicado: (2014)

Population-specific diversity of the immunoglobulin constant heavy G chain (IGHG) genes
por: Bashirova, Arman A., et al.
Publicado: (2021)

IMGT(®) Nomenclature of Engineered IGHG Variants Involved in Antibody Effector Properties and Formats
por: Lefranc, Marie-Paule, et al.
Publicado: (2022)

NKG2D and its ligands: active factors in the outcome of solid organ transplantation?
por: Suárez-Álvarez, Beatriz, et al.
Publicado: (2011)

Molecular mechanisms of postintensive care syndrome
por: Martín-Vicente, Paula, et al.
Publicado: (2021)

Characterization of Left Ventricular Non-Compaction Cardiomyopathy
por: Lorca, Rebeca, et al.
Publicado: (2020)

IGHG1 Regulates Prostate Cancer Growth via the MEK/ERK/c-Myc Pathway
por: Chu, Jing, et al.
Publicado: (2019)

Considering Computational Mathematics IGHG3 as Malignant Melanoma Is Associated with Immune Infiltration of Malignant Melanoma
por: Si, Mengqing, et al.
Publicado: (2022)

Chromosome Y Haplogroup R Was Associated with the Risk of Premature Myocardial Infarction with ST-Elevation: Data from the CholeSTEMI Registry
por: Lorca, Rebeca, et al.
Publicado: (2023)

The IFIH1/MDA5 rs1990760 Gene Variant (946Thr) Differentiates Early- vs. Late-Onset Skin Disease and Increases the Risk of Arthritis in a Spanish Cohort of Psoriasis
por: Coto-Segura, Pablo, et al.
Publicado: (2023)

Familial Hypercholesterolemia in Premature Acute Coronary Syndrome. Insights from CholeSTEMI Registry
por: Lorca, Rebeca, et al.
Publicado: (2020)

IGHG1 promotes malignant progression in breast cancer cells through the regulation of AKT and VEGF signaling
por: Zhang, Yong, et al.
Publicado: (2023)

Pharmacogenetics of tacrolimus: ready for clinical translation?
por: Coto, Eliecer, et al.
Publicado: (2011)

Spanish Adaptation of the Experiential Approach Scale (EAS)
por: Reyes-Martín, Salvador, et al.
Publicado: (2021)

Clinical Implications and Gender Differences of KCNQ1 p.Gly168Arg Pathogenic Variant in Long QT Syndrome
por: Lorca, Rebeca, et al.
Publicado: (2020)

Association of the Genetic Variation in the Long Non-Coding RNA FENDRR with the Risk of Developing Hypertrophic Cardiomyopathy
por: Cuesta-Llavona, Elías, et al.
Publicado: (2022)

Clinical Differences between Men and Women with Psoriatic Arthritis: Relevance of the Analysis of Genes and Polymorphisms in the Major Histocompatibility Complex Region and of the Age at Onset of Psoriasis
por: Queiro, Rubén, et al.
Publicado: (2013)

Opportunistic Genetic Screening for Familial Hypercholesterolemia in Heart Transplant Patients
por: Salgado, María, et al.
Publicado: (2023)

Clinical Evaluation of Patients with Genetically Confirmed Familial Hypercholesterolemia
por: Aparicio, Andrea, et al.
Publicado: (2023)

A Single Nucleotide Polymorphism in the Il17ra Promoter Is Associated with Functional Severity of Ankylosing Spondylitis
por: Vidal-Castiñeira, Jose Ramón, et al.
Publicado: (2016)

IGHG1 induces EMT in gastric cancer cells by regulating TGF-β/SMAD3 signaling pathway
por: Li, Yuxuan, et al.
Publicado: (2021)

Capillary electrophoresis of PCR fragments with 5´-labelled primers for testing the SARS-Cov-2
por: Gómez, Juan, et al.
Publicado: (2020)

Mitochondrial Heteroplasmy as a Marker for Premature Coronary Artery Disease: Analysis of the Poly-C Tract of the Control Region Sequence
por: Lorca, Rebeca, et al.
Publicado: (2023)

IGHG1 upregulation promoted gastric cancer malignancy via AKT/GSK-3β/β-Catenin pathway
por: Li, Xinyu, et al.
Publicado: (2021)

Implicit Attitudes to Female Body Shape in Spanish Women With High and Low Body Dissatisfaction
por: Hernández-López, Mónica, et al.
Publicado: (2019)

Soluble Co-Signaling Molecules Predict Long-Term Graft Outcome in Kidney-Transplanted Patients
por: Melendreras, Susana G., et al.
Publicado: (2014)

Validation of Spanish Erasmus-Modified Nottingham Sensory Assessment Stereognosis Scale in Acquired Brain Damage
por: Zamarro-Rodríguez, Belén Dolores, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_0mdoee2ef180bkb6p9op4tacse