AKR1C1 Protects Corneal Epithelial Cells Against Oxidative Stress-Mediated Ferroptosis in Dry Eye

PURPOSE: To evaluate the precise mode of cell death and to investigate the molecular mechanism underlying the initiation of inflammation in dry eye disease (DED). METHODS: C57BL/6 mice were injected with scopolamine subcutaneously and exposed to desiccating stress to establish a DED mouse model. An...

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Detalles Bibliográficos
Autores principales: Zuo, Xin, Zeng, Hao, Wang, Bowen, Yang, Xue, He, Dalian, Wang, Li, Ouyang, Hong, Yuan, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Cornea
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463717/
https://www.ncbi.nlm.nih.gov/pubmed/36066316
http://dx.doi.org/10.1167/iovs.63.10.3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463717/
https://www.ncbi.nlm.nih.gov/pubmed/36066316
http://dx.doi.org/10.1167/iovs.63.10.3

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