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An experimental model for ovarian cancer: propagation of ovarian cancer initiating cells and generation of ovarian cancer organoids

BACKGROUND: Ovarian cancer (OC) is the most lethal gynecological cancer due to the recurrence of drug-resistance. Cancer initiating cells (CICs) are proposed to be responsible for the aggressiveness of OC. The rarity and difficulty of in vitro long-term cultivation of CICs challenge the development...

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Detalles Bibliográficos
Autores principales: Chen, Yu-An, Lu, Chen-Yu, Cheng, Wen-Fang, Kuo, Kuan-Ting, Yu, Chen-Wei, Ho, Hon-Nerng, Chen, Hsin-Fu, Pan, Szu-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463800/
https://www.ncbi.nlm.nih.gov/pubmed/36085021
http://dx.doi.org/10.1186/s12885-022-10042-3