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Sperm DNA methylation alterations from cannabis extract exposure are evident in offspring

BACKGROUND: Cannabis legalization is expanding and men are the predominant users. We have limited knowledge about how cannabis impacts sperm and whether the effects are heritable. RESULTS: Whole genome bisulfite sequencing (WGBS) data were generated for sperm of rats exposed to: (1) cannabis extract...

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Detalles Bibliográficos
Autores principales: Schrott, Rose, Modliszewski, Jennifer L., Hawkey, Andrew B., Grenier, Carole, Holloway, Zade, Evans, Janequia, Pippen, Erica, Corcoran, David L., Levin, Edward D., Murphy, Susan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463823/
https://www.ncbi.nlm.nih.gov/pubmed/36085240
http://dx.doi.org/10.1186/s13072-022-00466-3