Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Sotagliflozin After Multiple Ascending Doses in Chinese Healthy Subjects

BACKGROUND: Sotagliflozin (LX4211) is a dual inhibitor of sodium-glucose cotransporter (SGLT)1 and SGLT2 being investigated to improve glycemic control in adults with diabetes. This study was firstly conducted to assess the pharmacokinetic (PK), pharmacodynamic (PD) profiles, safety and tolerability...

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Detalles Bibliográficos
Autores principales: He, Xuemei, Gao, Xin, Xie, Panpan, Liu, Yuan, Bai, Wenjing, Liu, Yue, Shi, Aixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464004/
https://www.ncbi.nlm.nih.gov/pubmed/36097559
http://dx.doi.org/10.2147/DDDT.S372575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464004/
https://www.ncbi.nlm.nih.gov/pubmed/36097559
http://dx.doi.org/10.2147/DDDT.S372575

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