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FLT3 Inhibitors as Maintenance Therapy after Allogeneic Stem-Cell Transplantation

Mutations in the FLT3 gene are associated with poor prognosis in patients with AML, even after consolidation with allogeneic hematopoietic cell transplantation (alloHCT) in first remission. Treatment failure in FLT3-mutated AML is largely driven by excessive risk of relapse compared to other genetic...

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Detalles Bibliográficos
Autores principales: Blackmon, Amanda, Aldoss, Ibrahim, Ball, Brian J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464008/
https://www.ncbi.nlm.nih.gov/pubmed/36097605
http://dx.doi.org/10.2147/BLCTT.S281252