Derivation of splice junction-specific antibodies using a unique hapten targeting strategy and directed evolution

Alternative splicing of RNA occurs frequently in eukaryotic cells and can result in multiple protein isoforms that are nearly identical in amino acid sequence, but have unique biological roles. Moreover, the relative abundance of these unique isoforms can be correlative with diseased states and pote...

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Detalles Bibliográficos
Autores principales: Fuller, Emily P., O’Neill, Rachel J., Weiner, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464090/
https://www.ncbi.nlm.nih.gov/pubmed/35750288
http://dx.doi.org/10.1016/j.nbt.2022.06.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464090/
https://www.ncbi.nlm.nih.gov/pubmed/35750288
http://dx.doi.org/10.1016/j.nbt.2022.06.003

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