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Derivation of splice junction-specific antibodies using a unique hapten targeting strategy and directed evolution
Alternative splicing of RNA occurs frequently in eukaryotic cells and can result in multiple protein isoforms that are nearly identical in amino acid sequence, but have unique biological roles. Moreover, the relative abundance of these unique isoforms can be correlative with diseased states and pote...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464090/ https://www.ncbi.nlm.nih.gov/pubmed/35750288 http://dx.doi.org/10.1016/j.nbt.2022.06.003 |