Make it double: identification and characterization of a Tandem-Hirudin from the Asian medicinal leech Hirudinaria manillensis

Haematophagous leeches express a broad variety of secretory proteins in their salivary glands, among them are hirudins and hirudin-like factors. Here, we describe the identification, molecular and initial functional characterization of Tandem-Hirudin (TH), a novel salivary gland derived factor ident...

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Detalles Bibliográficos
Autores principales: Lukas, Phil, Melikian, Georgij, Hildebrandt, Jan-Peter, Müller, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464118/
https://www.ncbi.nlm.nih.gov/pubmed/36006484
http://dx.doi.org/10.1007/s00436-022-07634-0