Cargando…

Single cell RNA sequencing confirms retinal microglia activation associated with early onset retinal degeneration

Mutations in the Membrane-type frizzled related protein (Mfrp) gene results in an early-onset retinal degeneration associated with retinitis pigmentosa, microphthalmia, optic disc drusen and foveal schisis. In the current study, a previously characterized mouse model of human retinal degeneration ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumari, Asha, Ayala-Ramirez, Raul, Zenteno, Juan Carlos, Huffman, Kristyn, Sasik, Roman, Ayyagari, Radha, Borooah, Shyamanga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464204/
https://www.ncbi.nlm.nih.gov/pubmed/36088481
http://dx.doi.org/10.1038/s41598-022-19351-w