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Characteristic distribution and molecular properties of normal cellular prion protein in human endocrine and exocrine tissues

Prion disease is an infectious and fatal neurodegenerative disease. Human prion disease autopsy studies have revealed abnormal prion protein (PrP(Sc)) deposits in the central nervous system and systemic organs. In deer, chronic wasting disease has also become a global problem, with PrP(Sc) in saliva...

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Detalles Bibliográficos
Autores principales: Koyama, Sachiko, Noguchi, Hideko, Yagita, Kaoru, Hamasaki, Hideomi, Shijo, Masahiro, Yoshimura, Motoi, Inoshita, Kohei, Sasagasako, Naokazu, Honda, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464206/
https://www.ncbi.nlm.nih.gov/pubmed/36088465
http://dx.doi.org/10.1038/s41598-022-19632-4