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Toll-like receptor 4-mediated endoplasmic reticulum stress induces intestinal paneth cell damage in mice following CLP-induced sepsis

A marked elevation of TLR4 was observed in various organs of septic mice. The mechanism of TLR4 in intestinal epithelial cell damage in sepsis remains unclear. CLP mice models were used to assess the role of TLR4 in intestinal Paneth cell damage by histological, polymerase chain reaction, western-bl...

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Detalles Bibliográficos
Autores principales: Wang, Yijie, Zhang, Dapeng, Li, Congxin, Wu, Xue, He, Chen, Zhu, Xiaolin, Zhao, Haiyan, Mu, Lingjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464222/
https://www.ncbi.nlm.nih.gov/pubmed/36088483
http://dx.doi.org/10.1038/s41598-022-19614-6