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PLGA-microspheres-carried circGMCL1 protects against Crohn’s colitis through alleviating NLRP3 inflammasome-induced pyroptosis by promoting autophagy

This study aimed to at explore exploring the biological functions of dysregulated circRNA in Crohn’s disease (CD) pathogenesis, with the overarching goal of and providing potential novel therapeutic targets. CircRNA microarray and quantitative real time-polymerase chain reaction (qRT-PCR) analyses w...

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Detalles Bibliográficos
Autores principales: Zhao, Jie, Sun, Ye, Yang, Haojun, Qian, Jun, Zhou, Yan, Gong, Yu, Dai, Yi, Jiao, Yuwen, Zhu, Weiming, Wang, Honggang, Lin, Zhiliang, Tang, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464224/
https://www.ncbi.nlm.nih.gov/pubmed/36088391
http://dx.doi.org/10.1038/s41419-022-05226-5