Synthesis, molecular docking, and pharmacological evaluation of 5-(4-(2-(5-ethyl pyridine-2-yl) ethoxy) benzyl)-3-(phenylsulfonyl) thiazolidine-2, 4-dione against HFD-induced diabesity via interaction with the CB1 receptor

OBJECTIVE(S): CB1 antagonism arbitrates a dormant shape to the endocannabinoid system that alleviates diverse pathological incidents of diabesity. The present study pursued the synthesis and evaluation of thiazolidine derivative (BAC) having pleiotropic action on CB1R, with or without AM251 (selecti...

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Detalles Bibliográficos
Autores principales: Deeba, Farah, Shahar Yar, Mohammad, Rafi Haidar, Mohammad, Sharma, Arun K., Sharma, Manju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464343/
https://www.ncbi.nlm.nih.gov/pubmed/36159331
http://dx.doi.org/10.22038/IJBMS.2022.65649.14443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464343/
https://www.ncbi.nlm.nih.gov/pubmed/36159331
http://dx.doi.org/10.22038/IJBMS.2022.65649.14443

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