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Knockdown of TRPM7 attenuates apoptosis and inflammation in neonatal necrotizing enterocolitis model cell IEC-6 via modulating TLR4/NF-κB and MEK/ERK pathways

OBJECTIVE(S): Neonatal necrotizing enterocolitis (NEC) is the most common gastrointestinal critical illness in neonatal infants. TRPM7 reportedly plays a role in human inflammatory bowel disease (IBD) and colorectal cancer, but the role of TRPM7 in the pathogenesis of NEC remains vague. MATERIALS AN...

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Detalles Bibliográficos
Autores principales: An, Lu, Li, Juan, Liu, Bing, Hui, Junpeng, Zhang, Qiang, Zhang, Xin, Wang, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464344/
https://www.ncbi.nlm.nih.gov/pubmed/36159330
http://dx.doi.org/10.22038/IJBMS.2022.62113.13742