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LOXL2 silencing suppresses angiotensin II-induced cardiac hypertrophy through the EMT process and TGF-β1/Smad3/NF-κB pathway

OBJECTIVE(S): Atrial fibrillation (AF) is a common arrhythmia with atrial myocyte hypertrophy linked with stroke, heart failure, and increased mortality. Lysyl oxidase-like 2 (LOXL2) involves the cross-linking of collagen in the extracellular matrix (ECM). In the present study, we investigated the r...

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Detalles Bibliográficos
Autores principales: Luo, Jun, Wu, Yingbiao, Zhu, Xi, Wang, Saihua, Zhang, Xiaogang, Ning, Zhongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464345/
https://www.ncbi.nlm.nih.gov/pubmed/36159334
http://dx.doi.org/10.22038/IJBMS.2022.63338.13981