AMP-activated protein kinase α2 contributes to acute and chronic hyperuricemic nephropathy via renal urate deposition in a mouse model

Hyperuricemia can induce acute and chronic kidney damage, but the pathological mechanism remains unclear. The potential role of AMP-activated protein kinase (AMPK) α2 in hyperuricemia-induced renal injury was investigated in this study. Acute and chronic hyperuricemic nephropathy was induced by admi...

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Detalles Bibliográficos
Autores principales: Yang, Chen, Su, Hong-yong, An, Ning, Wu, Hong-luan, Guo, Xiao-yan, Li, Zhi-hang, Chen, Xiao-cui, Zhu, Shao-ping, Wu, Dan, Li, Hui-yuan, Pan, Qing-jun, Liang, Dong, Liu, Hua-feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464416/
https://www.ncbi.nlm.nih.gov/pubmed/36088368
http://dx.doi.org/10.1186/s40001-022-00800-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464416/
https://www.ncbi.nlm.nih.gov/pubmed/36088368
http://dx.doi.org/10.1186/s40001-022-00800-1

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