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HLA-B evolutionary divergence is associated with outcomes after SARS-CoV-2 infection

We examined the correlation between class I HLA evolutionary divergence (HED), a surrogate for the capacity to present different peptides, and the outcomes of 234 adult inpatients with confirmed SARS-CoV-2 infection. Genomic DNA was extracted from peripheral blood and genotyped by next-generation se...

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Detalles Bibliográficos
Autores principales: Hernandez, Patricia V., Duffy, Brian, Hock, Karl, Farnsworth, Christopher, Schindler, Emily, Liu, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464580/
https://www.ncbi.nlm.nih.gov/pubmed/36109290
http://dx.doi.org/10.1016/j.humimm.2022.09.004