The collectin SP-A and its trimeric recombinant fragment protect alveolar epithelial cells from the cytotoxic and proinflammatory effects of human cathelicidin in vitro

Human cathelicidin (LL-37) is a defense peptide with antimicrobial activity against various pathogens. However, LL-37 can also trigger tissue injury by binding to host cell membranes. The cytotoxic effects of LL-37 may be especially relevant in chronic respiratory diseases characterized by increased...

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Detalles Bibliográficos
Autores principales: de Tapia, Lidia, García-Fojeda, Belén, Kronqvist, Nina, Johansson, Jan, Casals, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464622/
https://www.ncbi.nlm.nih.gov/pubmed/36105805
http://dx.doi.org/10.3389/fimmu.2022.994328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464622/
https://www.ncbi.nlm.nih.gov/pubmed/36105805
http://dx.doi.org/10.3389/fimmu.2022.994328

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