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Spatially Informed Cell Type Deconvolution for Spatial Transcriptomics

Many spatially resolved transcriptomic technologies do not have single-cell resolution but measure the average gene expression for each spot from a mixture of cells of potentially heterogeneous cell types. Here, we introduce a deconvolution method, conditional autoregressive deconvolution (CARD), th...

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Detalles Bibliográficos
Autores principales: Ma, Ying, Zhou, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464662/
https://www.ncbi.nlm.nih.gov/pubmed/35501392
http://dx.doi.org/10.1038/s41587-022-01273-7