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External validation: a simulation study to compare cross-validation versus holdout or external testing to assess the performance of clinical prediction models using PET data from DLBCL patients

AIM: Clinical prediction models need to be validated. In this study, we used simulation data to compare various internal and external validation approaches to validate models. METHODS: Data of 500 patients were simulated using distributions of metabolic tumor volume, standardized uptake value, the m...

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Detalles Bibliográficos
Autores principales: Eertink, Jakoba J., Heymans, Martijn W., Zwezerijnen, Gerben J. C., Zijlstra, Josée M., de Vet, Henrica C. W., Boellaard, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464671/
https://www.ncbi.nlm.nih.gov/pubmed/36089634
http://dx.doi.org/10.1186/s13550-022-00931-w