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Typical response of CD14(++)CD16(–) monocyte to knee synovial derived mediators as a key target to overcome the onset and progression of osteoarthritis

OBJECTIVE: Synovitis with increased infiltration of immune cells is observed in osteoarthritis (OA). Given the inflammatory condition of synovitis, we explored the protein profile of OA synovium (OAS) and its effect on circulating monocytes activation, migration, and functional commitments. METHODS:...

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Detalles Bibliográficos
Autores principales: Saffery, Nik Syazana Izyan, Genasan, Krishnamurithy, Chan, Chee Ken, Ayob, Khairul Anwar, Teo, Seow Hui, Al-Fayyadh, Mohamed Zubair Mohamed, Othman, Iekhsan, Abidin, Syafiq Asnawi Zainal, Raman, Murali Malliga, Raghavendran, Hanumantha Rao Balaji, Kamarul, Tunku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464827/
https://www.ncbi.nlm.nih.gov/pubmed/36106324
http://dx.doi.org/10.3389/fmed.2022.904721