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Interferon-gamma modulates articular chondrocyte and osteoblast metabolism through protein kinase R-independent and dependent mechanisms

Osteoarthritis (OA) affects multiple tissues of the synovial joint and is characterised by articular cartilage degeneration and bone remodelling. Interferon-γ (IFN-γ) is implicated in osteoarthritis pathology exerting its biological effects via various mechanisms including activation of protein kina...

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Detalles Bibliográficos
Autores principales: Gilbert, S.J., Blain, E.J., Mason, D.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464860/
https://www.ncbi.nlm.nih.gov/pubmed/36105611
http://dx.doi.org/10.1016/j.bbrep.2022.101323