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Integration of genomic variants and bioinformatic-based approach to drive drug repurposing for multiple sclerosis

Multiple sclerosis (MS) is a chronic autoimmune disease in the central nervous system (CNS) marked by inflammation, demyelination, and axonal loss. Currently available MS medication is limited, thereby calling for a strategy to accelerate new drug discovery. One of the strategies to discover new dru...

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Detalles Bibliográficos
Autores principales: Afief, Arief Rahman, Irham, Lalu Muhammad, Adikusuma, Wirawan, Perwitasari, Dyah Aryani, Brahmadhi, Ageng, Cheung, Rocky
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464879/
https://www.ncbi.nlm.nih.gov/pubmed/36105612
http://dx.doi.org/10.1016/j.bbrep.2022.101337