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Effects of zinc and carnosine on aggregation kinetics of Amyloid-β40 peptide

The accumulation and amyloid formation of amyloid-β (Aβ) peptides is closely associated with the pathology of Alzheimer's disease. The physiological environment wherein Aβ aggregation happens is crowded with a large variety of metal ions including Zn(2+). In this study, we investigated the role...

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Detalles Bibliográficos
Autores principales: Shen, Fengyun, Regmi, Deepika, Islam, Majedul, Raja Somu, Dawn, Merk, Vivian, Du, Deguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464885/
https://www.ncbi.nlm.nih.gov/pubmed/36105613
http://dx.doi.org/10.1016/j.bbrep.2022.101333