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Partial prevention of glucocorticoid-induced osteocyte deterioration in young male mice with osteocrin gene therapy
Glucocorticoid excess suppresses osteocyte remodeling of surrounding bone minerals, causes apoptosis of osteoblasts and osteocytes, and disrupts bone remodeling, eventually, leading to glucocorticoid-induced osteoporosis and bone fragility. Preventing apoptosis and preserving osteocyte morphology co...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464962/ https://www.ncbi.nlm.nih.gov/pubmed/36105586 http://dx.doi.org/10.1016/j.isci.2022.105019 |