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Resolving primary pathomechanisms driving idiopathic-like spinal curvature using a new katnb1 scoliosis model
Idiopathic scoliosis (IS) refers to abnormal spinal curvatures that occur in the absence of vertebral or neuromuscular defects. IS accounts for 80% of human spinal deformity, afflicts ∼3% of children worldwide, yet pathogenic mechanisms are poorly understood. A key role for cerebrospinal fluid (CSF)...
Autores principales: | Meyer-Miner, Anne, Van Gennip, Jenica L.M., Henke, Katrin, Harris, Matthew P., Ciruna, Brian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464966/ https://www.ncbi.nlm.nih.gov/pubmed/36105588 http://dx.doi.org/10.1016/j.isci.2022.105028 |
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