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β-hydroxybutyrate impairs monocyte function via the ROS-NLR family pyrin domain-containing three inflammasome (NLRP3) pathway in ketotic cows

Cows with ketosis display severe metabolic stress and immune dysfunction which renders them more susceptible to infections. Monocytes, one of the major subtypes of white blood cells, play an important role in innate immune defense against infections. Thus, the aim of this study was to investigate al...

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Detalles Bibliográficos
Autores principales: Dong, Zhihao, Sun, Xudong, Tang, Yan, Luo, Shengbin, Jia, Hongdou, Xu, Qiushi, Jiang, Qianming, Loor, Juan J., Xu, Wei, Xu, Chuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464975/
https://www.ncbi.nlm.nih.gov/pubmed/36105004
http://dx.doi.org/10.3389/fvets.2022.925900