System X(c) (−)/GSH/GPX4 axis: An important antioxidant system for the ferroptosis in drug-resistant solid tumor therapy

The activation of ferroptosis is a new effective way to treat drug-resistant solid tumors. Ferroptosis is an iron-mediated form of cell death caused by the accumulation of lipid peroxides. The intracellular imbalance between oxidant and antioxidant due to the abnormal expression of multiple redox ac...

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Detalles Bibliográficos
Autores principales: Li, Feng-Jiao, Long, Hui-Zhi, Zhou, Zi-Wei, Luo, Hong-Yu, Xu, Shuo-Guo, Gao, Li-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465090/
https://www.ncbi.nlm.nih.gov/pubmed/36105219
http://dx.doi.org/10.3389/fphar.2022.910292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465090/
https://www.ncbi.nlm.nih.gov/pubmed/36105219
http://dx.doi.org/10.3389/fphar.2022.910292

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