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Fluoxetine increases astrocytic glucose uptake and glycolysis in corticosterone-induced depression through restricting GR-TXNIP-GLUT1 Pathway

Antidepressant fluoxetine can affect cerebral glucose metabolism in clinic, but the underlying molecular mechanism remains poorly understood. Here, we examined the effect of fluoxetine on brain regional glucose metabolism in a rat model of depression induced by repeated corticosterone injection, and...

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Detalles Bibliográficos
Autores principales: Pan, Shu-Man, Zhou, Yi-Fan, Zuo, Na, Jiao, Rui-Qing, Kong, Ling-Dong, Pan, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465171/
https://www.ncbi.nlm.nih.gov/pubmed/36105196
http://dx.doi.org/10.3389/fphar.2022.872375