Case report: Phenotype expansion and analysis of TRIO and CNKSR2 variations

INTRODUCTION: TRIO and CNKSR2 have been demonstrated as the important regulators of RAC1. TRIO is a guanine exchange factor (GEF) and promotes RAC1 activity by accelerating the GDP to GTP exchange. CNKSR2 is a scaffold and adaptor protein and helps to maintain Rac1 GTP/GDP levels at a concentration...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Yuefang, Liang, Zhe, Cai, Weili, Shao, Qixiang, Pan, Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465251/
https://www.ncbi.nlm.nih.gov/pubmed/36105777
http://dx.doi.org/10.3389/fneur.2022.948877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465251/
https://www.ncbi.nlm.nih.gov/pubmed/36105777
http://dx.doi.org/10.3389/fneur.2022.948877

Ejemplares similares