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CRISPR/Cas9 targeted inactivation of the kauniolide synthase in chicory results in accumulation of costunolide and its conjugates in taproots

Chicory taproots accumulate sesquiterpene lactones lactucin, lactucopicrin, and 8-deoxylactucin, predominantly in their oxalated forms. The biosynthetic pathway for chicory sesquiterpene lactones has only partly been elucidated; the enzymes that convert farnesyl pyrophosphate to costunolide have bee...

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Detalles Bibliográficos
Autores principales: Cankar, Katarina, Hakkert, Johanna Christina, Sevenier, Robert, Campo, Eva, Schipper, Bert, Papastolopoulou, Christina, Vahabi, Khabat, Tissier, Alain, Bundock, Paul, Bosch, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465254/
https://www.ncbi.nlm.nih.gov/pubmed/36105709
http://dx.doi.org/10.3389/fpls.2022.940003