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Benchmarking DNA methylation analysis of 14 alignment algorithms for whole genome bisulfite sequencing in mammals

Whole genome bisulfite sequencing (WGBS) is an essential technique for methylome studies. Although a series of tools have been developed to overcome the mapping challenges caused by bisulfite treatment, the latest available tools have not been evaluated on the performance of reads mapping as well as...

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Detalles Bibliográficos
Autores principales: Gong, Wentao, Pan, Xiangchun, Xu, Dantong, Ji, Guanyu, Wang, Yifei, Tian, Yuhan, Cai, Jiali, Li, Jiaqi, Zhang, Zhe, Yuan, Xiaolong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465269/
https://www.ncbi.nlm.nih.gov/pubmed/36147684
http://dx.doi.org/10.1016/j.csbj.2022.08.051