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Using human urinary extracellular vesicles to study physiological and pathophysiological states and regulation of the sodium chloride cotransporter

The thiazide-sensitive sodium chloride cotransporter (NCC), expressed in the renal distal convoluted tubule, plays a major role in Na(+), Cl(-) and K(+) homeostasis and blood pressure as exemplified by the symptoms of patients with non-functional NCC and Gitelman syndrome. NCC activity is modulated...

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Detalles Bibliográficos
Autores principales: Wu, Aihua, Wolley, Martin J., Fenton, Robert A., Stowasser, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465297/
https://www.ncbi.nlm.nih.gov/pubmed/36105401
http://dx.doi.org/10.3389/fendo.2022.981317