Experimental study on the effects of simvastatin in reversing the femoral metaphyseal defects induced by sodium valproate in normal and ovariectomized rats

INTRODUCTION: Long-term treatment with antiepileptic drugs may cause secondary osteoporosis. The present study investigated the influence of simvastatin (SIM) in reversing the effects of valproate on bone defect healing in normal and ovariectomized (OVX) rats. METHODS: Bone defects in femora were es...

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Detalles Bibliográficos
Autores principales: Li, Yang, Zhang, Ruotian, Ren, Maoxian, Liu, Hedong, Yang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465351/
https://www.ncbi.nlm.nih.gov/pubmed/36105473
http://dx.doi.org/10.1016/j.heliyon.2022.e10480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465351/
https://www.ncbi.nlm.nih.gov/pubmed/36105473
http://dx.doi.org/10.1016/j.heliyon.2022.e10480

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