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Radiation induces ESCRT pathway dependent CD44v3(+) extracellular vesicle production stimulating pro-tumor fibroblast activity in breast cancer

Despite recent advances in radiotherapeutic strategies, acquired resistance remains a major obstacle, leading to tumor recurrence for many patients. Once thought to be a strictly cancer cell intrinsic property, it is becoming increasingly clear that treatment-resistance is driven in part by complex...

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Detalles Bibliográficos
Autores principales: Clark, Gene Chatman, Hampton, James David, Koblinski, Jennifer E., Quinn, Bridget, Mahmoodi, Sitara, Metcalf, Olga, Guo, Chunqing, Peterson, Erica, Fisher, Paul B., Farrell, Nicholas P., Wang, Xiang-Yang, Mikkelsen, Ross B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465418/
https://www.ncbi.nlm.nih.gov/pubmed/36106109
http://dx.doi.org/10.3389/fonc.2022.913656