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MutDock: A computational docking approach for fixed-backbone protein scaffold design

Despite the successes of antibodies as therapeutic binding proteins, they still face production and design challenges. Alternative binding scaffolds of smaller size have been developed to overcome these issues. A subset of these alternative scaffolds recognizes target molecules through mutations to...

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Detalles Bibliográficos
Autores principales: Chauhan, Varun M., Pantazes, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465448/
https://www.ncbi.nlm.nih.gov/pubmed/36106019
http://dx.doi.org/10.3389/fmolb.2022.933400