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Rho-Kinase inhibition decreases focal cerebral ischemia-induced glial activation in rats

BACKGROUND: Rho-kinase inhibition in a rat middle cerebral artery occlusion (MCAO) model is reported to improve neurological functions and decrease infarction size. OBJECTIVE: The objective of this study is to investigate the underlying mechanisms of such improvement by evaluating the effects of Rho...

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Detalles Bibliográficos
Autores principales: Sheikh, Abdullah Md, Yano, Shozo, Mitaki, Shingo, Tabassum, Shatera, Yamaguchi, Shuhei, Nagai, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465613/
https://www.ncbi.nlm.nih.gov/pubmed/36106069
http://dx.doi.org/10.1177/11795735221123910